An Open Labelled Parallel Comparative Clinical Study to evaluate the efficacy of Krakashdaladi Kwath and Navaka Guggulu in the management of Medodushti with special reference to Dyslipidemia
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the efficacy of Karkashdaladi kwath and Navak guggulu by applying appropriate stastical tools in the management of dyslipidemia.
研究概览
简要总结
Dyslipidemia can be corelated to medodushti as described inayurveda. Dyslipidemia is derangement of lipids.Dyslipidemia is highly prevalent and is one of modifiable risk factor for Diabetes mellitus, Obesity, Chronic heart Diseases, Thyroid Disorders. Modern statins are the medicine of choice for dyslipidemia, but they come with a long list of side effects. Therefore, seeking safe and efficient ayurveda treatment is necessary for a better solution. Karkashdaladi kwath has all the properties that are useful to produce Strotovishodhana*,* AamapachanaandLekhanofMedaandsohasNavakGuggulu*.* A study aimed at comparing the efficacy of Karkashdaladikwath and NavakGuggulu will be carried out on patients who will be randomly selected and divided in two groups having 30 patients in each group. In group A (30 patients) karkashdaladi kwath (50ml) will be given after meal with water and In group B (30 patients) Navak guggulu (500mg) will be after meal with for 28 days. Patients will be followed up at regular interval of 7 days during the course of therapy to assess variation in symptomatology and to know any complication. Subjective and objective criteria will be analysed during and post treatment. The work will be compiled and the outcome will be drawn using statistical data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients willing to sign the consent form.2.Patients between the age group of 25-45 years of either gender.3.Patients having underweight, normal weight, overweight, and class I obesity according to BMI.4.Diagnosed & confirmed cases of Medodushti (Dyslipidemia) & Medoroga on the basis of criteria given by NCEP-ATPIII.
- •(Borderline High category).
排除标准
- •a) Patient not fulfilling inclusion criteria.
- •b) Patient not willing for clinical trial.
- •c) Patient below 25yrs of age group and above 45yrs of age group.
- •d) Patients having medical history of – CAD, CKD, AKD, Uncontrolled Diabetes Mellitus, Uncontrolled Hypertension.
- •e) Patient on steroid therapy and oral contraceptive therapy.
- •f) Pregnant women and lactating mothers.
结局指标
主要结局
To assess the efficacy of Karkashdaladi kwath and Navak guggulu by applying appropriate stastical tools in the management of dyslipidemia.
时间窗: 28 days
次要结局
- 1. Reduction in weight, BMI, Serum cholesterol, Serum triglycerides, LDL, VLDL, and an increase in Serum HDL.(2. Reduction in scoring pattern of sign and symptoms of Medorog)
研究者
Dr Charu Walia
Institute for Ayurved Studies and Research, SKAU, Kurukshetra