NCT03614312已完成不适用
Epigenetic Mechanisms Underlying Trophoblast Syncytialization
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Number of participants that placental syncytial fusion involves epigenetic changes in histone modifications
研究概览
简要总结
This study will help us learn more about how the placenta develops.
详细描述
The primary purpose of this study is to understand the epigenetic signaling events in placental trophoblast development.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI - 18-25 kg/m2
- •at least 18 years of age
- •singleton pregnancy
- •less than 36 weeks and plan to deliver in the Little Rock/North Little Rock Area
排除标准
- •Women with pre-existing medical conditions (e.g. diabetes, hypertension, pre-eclampsia, STD, gestational diabetes)
- •Women who are using recreational drugs, tobacco, or alcohol during their pregnancy.
- •Women who plan on keeping their placenta following delivery for non-medical reasons.
结局指标
主要结局
Number of participants that placental syncytial fusion involves epigenetic changes in histone modifications
时间窗: 40 weeks
Number of participants that histone acetyltransferases eszymes, CBP and p300 affect syncytial fusion
次要结局
未报告次要终点
研究者
研究点 (1)
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