Corneal Thickness and Corneal Endothelial Cell Loss after Phacoemulsification in Different Grades of Nuclear Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess Corneal thickness and Corneal endothelial cell loss after Phacoemulsification in different grades of Nuclear sclerosis
研究概览
简要总结
Cataract is a major and the biggest cause of treatable blindness worldwide .
Phacoemulsification is considered nowadays the surgery of choice for cataract removal worldwide.
Phacoemulsification surgery can cause corneal endothelial cell loss owing to the dissipated ultrasound energy during the procedure.
Exaggeration of corneal endothelial cell loss can lead to postoperative complications such as delayed regression of corneal edema or even permanent edema of the cornea or bullous keratopathy
Loss of endothelial function by the damage of endothelial cells can lead to increased corneal thickness and decreased corneal transparency because of increased stromal hydration due to compromised pump function .
So my Aim is to study Corneal thickness and Corneal endothelial cell loss after Phacoemulsification in different grades of Nuclear sclerosis
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 50.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patients ready to give written informed consent.
- •2 Patient WITH CATARACT, 50 to 70 years of age, both sexes with no prior ocular disease, 3 Clear cornea devoid of any corneal dystrophy and degenerations, undergoing routine phacoemulsification surgery, 4 Patients with corneal ECD of more than 2000 cellmm.
排除标准
- •1 Preoperative endothelial count less than 2000 cellsmm, 2 Any type of corneal pathology such as corneal degeneration and corneal dystrophy, contact lens wear history.
- •3 Any complicated cataract other than senile nuclear cataract are excluded.
- •4 Previous ocular surgeries,trauma ,chronic glaucoma 5 Patients with inadequate follow-up.
结局指标
主要结局
To assess Corneal thickness and Corneal endothelial cell loss after Phacoemulsification in different grades of Nuclear sclerosis
时间窗: Preoperative | Postoperative 1st week | Postoperative 1st month
次要结局
- NILL(NILL)
研究者
Dr Aparna Reddy
Sankara Eye Hospital