Corneal Endothelial Evaluation After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Corneal Endothelial Cell Loss
- Sponsor
- Minia University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- corneal endothelial cell loss
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
Detailed Description
In a prospective interventional case-control study, 20 eyes with cataract and PEX and 20 control eyes with cataract without PXE were subjected to phacoemulsification and posterior chamber foldable intraocular lens implantation in Minia University Hospital and Genaidy Eye Center between March 2019 and December 2020. Specular microscopy was done preoperatively, 3 and 6 months postoperatively. Endothelium cell density (ECD), coefficient variation (CV), hexagonality, pleomorphism and corneal thickness were evaluated and compares between PXE and control eyes.
Investigators
Hosny Ahmed Zein
Assistant Professor
Minia University
Eligibility Criteria
Inclusion Criteria
- •senile cataract age more than 55 years
Exclusion Criteria
- •PEX with glaucoma, eyes with cornea guttata or any corneal dystrophy, zonular dehiscence, very dense nuclear cataract (cataracta nigra) history of previous ocular surgery.
Outcomes
Primary Outcomes
corneal endothelial cell loss
Time Frame: 6 months
corneal endothelial cell loss