use of mifepristone for induction of labor in women with previous one low segment cesarean section comparison with mechanical stretching of cervix

Not Applicable

Completed

• Conditions: Health Condition 1: null- pregnant patients 40 weeks gestation with single cephalic pregnancy & previous one low segment cesarean section

• Registration Number: CTRI/2012/06/002733
• Lead Sponsor: DR RAJENDRA PRASAD GOVERNMENT MEDICAL COLLEGE KANGRA AT TANDA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-09-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 107

Inclusion Criteria

•Singleton pregnancy

•Previous one low segment cesarean section, no other uterine scar or previous rupture

•Gestation beyond 40 weeks

•Cephalic presentation

Exclusion Criteria

•Inter-conceptional period less than 18 months

•Estimated fetal birth weight > 4kg

•Poor modified bio-physical profile

(Amniotic fluid index < 5 cm or non-reassuring non stress test)

•Poor dating ( not sure of dates, no ultrasonography in first trimester or two serial ultrasounds 4 weeks apart in second trimester)

•Premature rupture of membranes/ chorio-amniotis

•Premature rupture of membranes/ chorio-amniotis

•Evidence of fetal distress at admission

•Intra-uterine fetal death

•Any maternal disease ie hypertension, diabetes, renal disease, liver disease, cardiac disease, epilepsy or any chronic medication

•Any contraindication for vaginal delivery ( cephalo-pelvic disproportion ruled out)

•Type of caesarean section not known ( classical or low segment)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the proportion of women entering labor after use of mifepristone alone as compared to sweeping stretching of cervix or use of trans-cervical folleyâ??s catheter.Timepoint: 48 hours after intervention & subsequently delivery of fetus

Secondary Outcome Measures

Name	Time	Method
â?¢Proportion of women vaginally delivered in each group <br/ ><br>â?¢Proportion of women with cesarean section in each group <br/ ><br>â?¢Duration of labor in women in each group <br/ ><br>â?¢Need and amount of oxytocin required in each group <br/ ><br>â?¢Proportion of women with scar dehiscence/ rupture in each group <br/ ><br>â?¢Neonatal outcomes <br/ ><br>â?? <br/ ><br>Timepoint: 48 hours