Epidemiological and Clinical Characteristics of Hospitalized Patients Under 5 Years Old With RSV Infection in Central China, Wuhan

• Conditions: RSV Infection

• Registration Number: NCT05767294
• Lead Sponsor: Tongji Hospital

Brief Summary

The study will be a multicenter, hospital-based retrospective study. We plan to collect the clinical and laboratory data among all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then analyze the epidemiological and clinical characteristics of RSV infection, clarify the gene types of epidemics under 5 years old children after the outbreak in Wuhan, China.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-02-16
• Study First Submitted QC: 2023-03-01
• Study First Posted: 2023-03-14
• Study Start: 2023-12-05
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-19
• Last Update Posted: 2024-04-22
• Primary Completion: 2024-12-31
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

①Admission age <5 years old

②Clinical diagnosis of acute respiratory tract infections

Exclusion Criteria

Hospital acquired ARTI

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
number of patients with fever	at admission	number of patients with fever
number of patients with underlying disease	at admission	underlying disease include immune deficiency, CHD, BPD, BO, bronchiectasis and asthma and so on
number of patients with treatment of immunoglobulin	through study completion, an average of 1 year	number of patients with treatment of immunoglobulin
number of patients with treatment of glucocorticoids	through study completion, an average of 1 year	number of patients with treatment of glucocorticoids
proportion of different virus genotype	through study completion, an average of 1 year	virus genotype include A, B and C
number of patients infected with virus	through study completion, an average of 1 year	number of patients infected with virus
number of patients with cough	at admission	number of patients with cough
number of patients with shortness of vomit	at admission	number of patients with shortness of vomit
number of patients with shortness of rale	at admission	number of patients with shortness of rale
number of patients with treatment of ventilation	through study completion, an average of 1 year	number of patients with treatment of ventilation
direct medical cost	through study completion, an average of 1 year	direct medical cost
F protein gene sequence	through study completion, an average of 1 year	F protein gene sequence
number of patients with shortness of breath	at admission	number of patients with shortness of breath
number of patients with treatment of antibiotic	through study completion, an average of 1 year	number of patients with treatment of antibiotic
number of patients with shortness of wheeze	at admission	number of patients with shortness of wheeze
number of patients with shortness of stridor	at admission	number of patients with shortness of stridor
age	at admission	age
Imaging examination results	through study completion, an average of 1 year	X-Ray/CT
length of hospital stay length of stay length of stay	through study completion, an average of 1 year	length of hospital stay
number of patients with treatment of oxygen inhalation	through study completion, an average of 1 year	number of patients with treatment of oxygen inhalation
number of patients infected with bacteria	through study completion, an average of 1 year	number of patients infected with bacteria
number of patients infected with fungus	through study completion, an average of 1 year	number of patients infected with fungus
gender	at admission	female/male

Trial Locations

Locations (1)

department of pediatrics, Tongji hospital, Tongji medical college, Huazhong University of Science and Technology; 🇨🇳 Wuhan, Hubei, China