Factors Predicting Erythropoietin Responsiveness in Children on Hemodialysis at Sohag University Hospital
- Conditions
- Pediatric Patients on Hemodialysis
- Interventions
- Diagnostic Test: seum zinic,vit B12, parathyriod function
- Registration Number
- NCT05312346
- Lead Sponsor
- Sohag University
- Brief Summary
Anemia is common in patients on hemodialysis (HD) due to lack of erythropoietin (EPO) synthesis and iron deficiency is occurring in HD patients due to chronic blood loss through the dialysis circuit, repeated blood sampling, shortened red blood cell life span and lack of adherence to treatment .
Anemia is one of the most important complications that affects morbidity and mortality in chronic kidney disease (CKD) patients. It has significant impacts on those patients such as fatigue, weakness, shortness of breath, decreased quality of life, exercise capacity and physical activity, growth retardation and decreased cognitive functions, left ventricular hypertrophy, and congestive heart failure So, proper management of anemia is very important .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- (1) patients started dialysis in the age range of 1-18years. (2) Patient will be on regular hemodialysis.
- Children who have no other co existent hematological disorder .
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description responsiveness to erythropoietin stimulating agent seum zinic,vit B12, parathyriod function we evolute responsiveness of patients on hemodialysis for erythropoietin stimulating agents or not and factors effecting this response
- Primary Outcome Measures
Name Time Method Serum creatinine one year serum creatinine
Hb g/dl one year measure hemoglobin level
Iron profile one year measure iron profile on blood
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sohag University Hospital
🇪🇬Sohag, Egypt