CTRI/2018/02/012190已完成4 期
Effect of preoperative chronic phenytoin versus levetiracetam therapyon neuromuscular block following atracurium or vecuronium
SCTIMST Hospital0 个研究点目标入组 40 人开始时间: 待定最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. ASA grade I or II undergoing neurosurgery under general
- •anesthesia.
- •2. Age 18-60 years, of either sex, who have the ability to give informed consent.
- •3. On chronic ( >7 days) phenytoin or levetiracetam therapy
排除标准
- •1. Pre-existing neuromuscular disease
- •2. Prolonged administration of neuromuscular blocker
- •3. Any other drug known to affect neuromuscular function
- •4. Peripheral neuropathies
- •5. Prolonged immobility
- •6. Following major burns upto 2 years
- •7. Liver disease
- •8. Kidney disease
- •9. Cardiac disease
- •10. Pregnancy
- •11. Pre-existing or intraoperative acid-base disorder
- •12. Electrolyte imbalances such as hyper/hypokalemia, hyper/hypocalcemia,
- •hyper/hypomagnesemia, hyper/hyponatremia
- •13. Endocrinopathies
- •14. Patient refusal
研究者
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