ISRCTN28828586已完成不适用
AcetylCysteine in the treatment of Sickle Cell Disease
CURAMA Study Group (The Netherlands)0 个研究点目标入组 10 人开始时间: 2007年8月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. High performance liquid chromatography confirmed diagnosis of sickle cell anaemia (HbSS), sickle-haemoglobin C disease (HbSC) or sickle cell trait disease (HbSa) genotype
- •2. Aged 18 to 65 years
- •3. Written informed consent
排除标准
- •1. Blood transfusion in the preceding four months
- •2. Pregnancy or the desire to get pregnant in the following seven months
- •3. Concomitant use of hydroxyurea, vitamin K antagonists or other oral anticoagulants, or contraindications for NAC
- •4. Impaired renal function of more than 60% (as assessed by the Kockroft-Gauld equation)
- •5. Known gastric or duodenal ulcer
- •6. Concomitant use of anti-hypertensives, sildefanil or nitrates
研究者
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