EUCTR2006-005889-40-NL进行中（未招募）不适用
Acetylcysteine for Treatment of Sickle Cell Disease - N-acetylcystein for Sickle Cell Disease
Academic Medical Centre0 个研究点目标入组 10 人开始时间: 2006年11月2日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Ten patients with SCD (HbSS HbSC or HbSb) will be included.
- •Inclusion criteria
- •1.High performance liquid chromatography confirmed diagnosis of HbSS HbSC or HbSb genotype
- •2.Aged 18-65 years
- •3.Written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Exclusion criteria
- •1.Bloodtransfusion in the preceding four months
- •2.Pregnancy or the desire to get pregnant in the following 7 months
- •3.Concommitant use of hydroxyurea, vitamin K antagonists or other oral anticoagulants, or contraindications for NAC.
- •4.Impaired renal function of more than 60% (as assessed by the Kockroft-Gauld equation)
- •5.Known gatsric or duodenal ulcer
- •6.Concomittant use of anti-hypertensives, sildefanil or nitrates.
研究者
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