Evaluation of Using Sticky Bone Grafting Combined With Concentrated Growth Factor Membrane for Repair of Unilateral Alveolar Cleft
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- inflammation
研究概览
简要总结
The aim of this study is to evaluate using Sticky Bone grafting combined with concentrated growth factor membrane for repair of unilateral alveolar cleft.
详细描述
This study will be carried out on ten patients with unilateral alveolar clefts, The patients will be recieved, clinically& radiographically examined and managed at Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Tanta University.
Preoperative evaluation:
Clinical evaluation will include presence of oronasal fistulas, nasal regurgitation and Presence of erupting teeth in cleft. .Preoperative cone beam computed tomography (CBCT) scans will be analyzed to measure alveolar cleft dimensions and the total cleft defect volume will be calculated.
Surgical technique:
Under general anesthesia, mucoperiosteal flaps will be raised along the cleft margins, exposing the defect. The nasal lining will be sutured with 4/0 Vicryl, followed by the application of a concentrated growth factor (CGF) membrane to cover the nasal mucosa. The sticky bone graft will be packed tightly into the cleft, ensuring complete defect filling. A CGF membrane will be then placed over the graft to enhance stability and healing. The flaps will be sutured using tension-free interrupted 3/0 Vicryl sutures to ensure full coverage of the graft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with unilateral alveolar clefts requiring repair.
- •patients free from any systemic disease that may affect normal healing of bone.
- •patients at an age older than 12 years
排除标准
- •Bilateral alveolar clefts.
- •Immunocompromised patients.
- •Syndromic patients.
研究组 & 干预措施
Sticky Bone grafting with concentrated growth factor membrane for unilateral alveolar cleft
This will include 10 patients in whom unilateral alveolar cleft will be repaired using sticky bone grafting combined with concentrated growth factor membrane
干预措施: Unilateral alveolar cleft repair (Procedure)
结局指标
主要结局
inflammation
时间窗: 1 month
mild, moderate, severe
nasal regurgitation
时间窗: 1 month
Yes or No
fistula recurrence
时间窗: 1 month
positive or negative
bone mineral density
时间窗: 1 month
soft ware
bone graft volume
时间窗: 1 month
soft ware
次要结局
- bone graft volume(9 months)
- bone mineral density(9 months)
研究者
Maram Nashaat Breshah
Lecturer of Oral & Maxillofacial Surgery
Tanta University