Evaluation of indigenously prepared sticky bone in the management of endo- perio lesions: A clinical study
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Changes in probing depth in the defect site. Changes in clinical attachment level in the defect site. Changes in the bone fill.
研究概览
简要总结
To evaluate the clinical outcome of sticky bone autologous concentrated growth factor enriched indigenously prepared bone graft matrix for the management of endo-perio lesions. The use of an osseograft combined with CGF has numerous advantages owing to the formation of sticky bone. The product thus formed can be molded, prevent both macro and micro movements, also the network is proven to contain platelets and growth factors thereby contributing to accelerated soft tissue healing and bone regeneration. Furthermore, the fibrin interconnection prevents the ingrowth of soft tissue into the bone graft as well. A thorough search of the literature disclosed the absence of any publication with reference to the use of sticky bone in endodontic surgical procedures, thus highlighting the uniqueness of this study in that regard
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects of either sex between the age group 18 to 55 years who are willing to sign written consent for the study.
- •Subjects having atleast one tooth having periodontal pocket greater than 6mm and periapical involvement.
- •Subjects having persisting periodontal pocket post 3 month of endodontic treatment.
- •Subjects having radiographic evidence of vertical bone loss greater than 4 mm.
排除标准
- •1.Teeth with root caries .
- •2.History of surgery in the respective tooth in the last 6 months.
- •3.Uncontrolled systemic diseases (e.g. uncontrolled diabetes, uncontrolled hypertension , bleeding disorders).
- •4.Pregnant or lactating woman.
结局指标
主要结局
Changes in probing depth in the defect site. Changes in clinical attachment level in the defect site. Changes in the bone fill.
时间窗: At baseline, 1 month, 6 month
次要结局
- To assess the clinical adverse effects of the grafts, if any.(At baseline, 1 month, 6 month)
