FSH-R : Diagnostic Application for Localized Tumors in Cancerology
Not Applicable
Terminated
- Conditions
- Cancer
- Interventions
- Procedure: blood sample for FSHR analysis
- Registration Number
- NCT02860481
- Lead Sponsor
- Institut Curie
- Brief Summary
FRACTal study is the first exploration of detection of FSHR as a blood biomarker for the diagnosis of cancer.
A first cohort will explore several common (e.g. breast, prostate) or rare (e.g. uveal melanoma) cancers, that are frequently treated at Institut Curie. This first cohort will include n=10 patients per histological type except for breast cancer (n=50). 100 patients are expected in this cohort.
A second cohort will explore the more promising histological type (if any) in term of incidence of detection. 100 patients are expected for this second cohort.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 95
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description second cohort : 100 patients blood sample for FSHR analysis Patients with breast cancer of with ovarian and/or endometrial cancer first cohort : first 100 patients blood sample for FSHR analysis first cohort : first 100 patients 10 patients with ovarian and/or endometrial cancer 10 patients with colorectal cancer 10 patients with head and neck cancer 10 patients with uveal melanoma 40 patients with invasive breast cancer 10 patients with breast ductal carcinoma in situ 10 patients with other tumor type
- Primary Outcome Measures
Name Time Method sensitivity of blood FSH R detection in cancer patients end of the study, up to two years
- Secondary Outcome Measures
Name Time Method comparison of blood FSH-R with blood from healthy donor end of the study, up to two years variability of blood FSH-R in the same tumoral type and between different tumoral types end of the study, up to two years
Trial Locations
- Locations (2)
Centre René Huguenin
🇫🇷Saint Cloud, France
Institut Curie
🇫🇷Paris, France