Relative contribution of trends in cardiovascular disease event rates and case fatality to declines in mortality: an international population-based comparative study

Not Applicable

Completed

• Conditions: Cardiovascular disease; Cardiovascular - Coronary heart disease; Stroke - Ischaemic; Stroke - Haemorrhagic; Public Health - Epidemiology

• Registration Number: ACTRN12621000026820
• Lead Sponsor: niversity of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-01-09
• Study Start: 2021-01-14
• Last Update Posted: 18 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3000000

Inclusion Criteria

All hospitalisations and deaths which meet the specific requirements for each condition, based on International Classification of Disease coding, diagnosis or cause of death fields, and time period (admissions and deaths occurring between 01 January 2002 and 31 December 2015).

Exclusion Criteria

Criteria will be imposed which exclude patients with low probability of a major cardiovascular event, such as short length of stay and elective admissions for acute events such as myocardial infarction or stroke.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardiovascular disease mortality.<br>This outcome will be obtained from linked mortality datasets from each jurisdiction. Each dataset contains all CVD deaths from 2002 to 2015 and includes deaths in people hospitalised with CVD and CVD deaths occurring out of hospital.[Annual CVD mortality rates.<br>Annual cardiovascular disease mortality rates from 2002-2015 will be estimated following receipt of full study datasets.];CVD event rates (composite of nonfatal and fatal CVD events).<br>This outcome will be obtained from linked hospitalisation and mortality datasets from each jurisdiction. Each dataset contains all CVD hospitalisations and deaths from 2002 to 2015 and includes deaths in people hospitalised with CVD and CVD deaths occurring out of hospital.[Annual CVD event rates.<br>Annual cardiovascular disease event rates from 2002-2015 will be estimated following receipt of full study datasets.]