Cardiovascular development and function in relation to nuchal translucency.

• Conditions: increased nuchal translucency; nuchal fold.; 10010394; 10083624; 10016849

• Registration Number: NL-OMON29933
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

group 1: singleton pregnancy
Crown Rump Length between 45 mm and 79 mm.
increased nuchal translucency (> p 95)
group 2: singleton pregnancy
Crown Rump Length between 45 mm and 79 mm.
nuchal translucency < p 95

Exclusion Criteria

twin pregnancy
Crown Rump Length smaller than 45 mm or bigger than 79 mm.;use of teratogenical medication
skeletal dysplasia of the fetus

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences in cardiac function between fetuses with normal nuchal translucency<br /><br>and fetuses with increased nuchal translucency.<br /><br><br /><br>Differences in cardiovascular development between wild type mouse embryo's and<br /><br>trisomy 16 mouse embryo's/ VEGF 120/120 mouse embryo's.<br /><br><br /><br>Differences in cardiovascular development between human fetuses with normal<br /><br>nuchal translucency and increased nuchal translucency.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>