Cardiovascular characteristics of the healthy children, adolescents and young adults during simulated short-term exposure to high altitude
Not Applicable
Recruiting
- Conditions
- Physiologic changes in healthy volunteers
- Registration Number
- DRKS00032016
- Lead Sponsor
- udwig Maximilian Universität
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
healthy volunteers
Exclusion Criteria
Significant heart, lung, rheumatological or oncological disorders. Patients who are unable to provide informed consent or are not able to participate in spiroergometry.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is the aim of this study to evaluate the acute effect of normobaric hypoxia on heart and vasculature (arterial stiffness, microcirculation) in health children and young adults age 8-28 years, using a multimodal approach.<br>- right ventricular pressure and function
- Secondary Outcome Measures
Name Time Method - Left ventricular SF, E', E/E'<br>- VO2<br>- central Blutdruck, Augmentation index, Pulse Wave Velocity<br>- Aging index<br>- retinal arteriolar-to-venular diameter ratio (AVR) (static retinal analyser)