Comparison of non-invasive positive pressure ventilation for extubated patients who fail a single spontaneous breathing trial vs conventional weaning

Not Applicable

Completed

• Conditions: Respiratory: Positive pressure ventilation; Respiratory; Positive pressure ventilation

• Registration Number: ISRCTN32810409
• Lead Sponsor: Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09-28
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

1. Patients will need to meet the criteria for reducing breathing support - will not be weaned until physiologically ready.
2. Patients will have to be on a breathing machine attached to a tube in the mouth for at least 48 hours - patients who are on a breathing machine for <48 hours are not seen as difficult to wean from a ventilator
3. Age > 18 years - patient should be able to make own legal judgements to treatment
4. Written informed consent obtained - unethical to carry out study without consent
5. Failed an attempt to try breathing without help - study only being carried out on people who have difficulty with weaning

Exclusion Criteria

Added September 2008:
1. Patients who are generally not suitable for noninvasive ventilationGrade III/IV intubation
2. Gastric/oesophageal surgery on this admission
3. Patients who it has been decided would not be for re-intubation once extubated

Study & Design

• Study Type: Interventional
• Study Design: Not specified