Effectiveness of Non-invasive Ventilation in patients with asthma
Phase 2
- Conditions
- asthma.Acute severe asthma
- Registration Number
- IRCT2017021427929N4
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Age between 18-75 years; dyspnea; peak expiratory flow <200cc; respiratory rate >24/minute; confirmed diagnosis of asthma; receiving standard asthma treatment.
Exclusion criteria: Chronic obstructive pulmonary disease; unstable vital signs such as systolic blood pressure <90 mmHg after liquid therapy; patient unwillingness to participate in the study; decrease in level of consciousness; acute myocardial infarction or ischemic heart failure; pH<7.10; unable to use mask; inability to clean airway secretions.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Forced expiatory volume in 1st second. Timepoint: Before and after intervention. Method of measurement: spirometry.
- Secondary Outcome Measures
Name Time Method Arterial PO2. Timepoint: Before and after intervention. Method of measurement: arterial blood gas.;Arterial PCO2. Timepoint: Before and after intervention. Method of measurement: arterial blood gas.;Blood pressure. Timepoint: Before and after intervention. Method of measurement: Clinical counting.;Heart rate. Timepoint: Before and after intervention. Method of measurement: Clinical counting.;Dyspnea. Timepoint: Before and after intervention. Method of measurement: Dyspnea Borg Scale.