Postprandial Blood Cell Transcriptome of Normal Weight and Obese Subjects to 3 Caloric Doses of a High-fat Meal

Not Applicable

Completed

• Conditions: Obesity; Nutritional Intervention

• Registration Number: NCT01995110
• Lead Sponsor: Agroscope Liebefeld-Posieux Research Station ALP

Brief Summary

The study will quantitatively evaluate the metabolic response of normal weight and obese subjects to three high-fat meals differing in caloric dose by analysing the postprandial blood transcriptome.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Primary Completion: 2012-08
• Study Completion: 2013-11
• Study First Submitted: 2013-11-21
• Study First Submitted QC: 2013-11-21
• Study First Posted: 2013-11-26
• Status Verified: 2014-04
• Last Update Submitted: 2014-04-23
• Last Update Posted: 2014-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 14

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
blood cell transkriptome/ gene-expression	0h, 2h, 4h, 6h	* differently expressed genes between normal weight and obese subjects at baseline; * changes in gene-expression 2, 4 and 6h after consumption

Trial Locations

Locations (2)

Agroscope; 🇨🇭 Berne, Switzerland

University Hospital Inselspital Berne; 🇨🇭 Berne, Switzerland