Randomized Clinical Trial of 8 Weeks Pulmonary Rehabilitation in Advanced Stage Lung Cancer Patients With COPD During Cytotoxic Chemotherapy

Not Applicable

Brief Summary: Pulmonary rehabilitation might be benificial in advanced lung cancer patients with COPD who undergo cytotoxic chemotherapy.

We will compare two groups, 8 week pulmonary rehabilitation group and usual care group.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

other history of cancer within 5 years
other major disease associated with heart, lung, neurology, mental and metabolic disorders
osteolytic bone metastatis to weight bearing site
uncontrolled infection

Arm && Interventions

Group	Intervention	Description
pulmonary rehablitation	pulmonary rehabilitation	warming up exercise strengthening exercise aerobic exercise cool down

Primary Outcome Measures

Name	Time	Method
difference of VO2 max	8 weeks	difference maximal oxygen consumption during exercise cardiopulmonary test between before and after intervention/control

Secondary Outcome Measures

Name	Time	Method
difference of Saint George's Respiratory Questionannaire (SGRQ) score	8 weeks	the difference of SGRQ score
difference of pulmonary function test	8 weeks	the difference of FVC and FEV1
difference of 6 min walk test	8 weeks	the difference of 6 minute walk test
difference of depression test	8 weeks	using Hospital Anxiety and Depression scale (HADS), measure the difference HADS between before and after intervention/control

Locations (1): Seoul National University Hospital
🇰🇷
Seoul, Korea, Republic of

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