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Evaluation of autonomic control of heart rate in older male patients with chronic obstructive pulmonary disease or chronic heart failure at rest and during sinusal respiratory arrhythmia maneuver

Not Applicable
Completed
Conditions
Autonomic control of heart rate
Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system
Registration Number
ACTRN12609000467235
Lead Sponsor
Federal University of Sao Carlos
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
30
Inclusion Criteria

Inclusion criteria for COPD patients were: forced expiratory volume in one second (FEV1) / forced vital capacity (FVC) ratio < 0.7 and FEV1 < 60% of predicted; clinical stability for at least 3 months prior to the study; nonsmokers; no participation in a regular physically active program in for the last 6 months; and presentation of dyspnea under low and medium physical effort. Inclusion criteria for CHF patients were: previous history of stable symptomatic heart failure due to left ventricular systolic dysfunction, documented in at least six months (left ventricular ejection fraction < 45 % predict); no recent hospitalizations and no history of pulmonary disease or angina. Subjects in the control group were free of chronic pulmonary, cardiovascular, immune, and metabolic disease.

Exclusion Criteria

unstable patients, female, patients without clinical exams

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The respiratory sinusal arrhythmia maneuver is able to characterize the changes of autonomic activity in the control of heart rate.[All evaluated were performed at the same day.]
Secondary Outcome Measures
NameTimeMethod
The heart rate variability at rest is able to characterize the changes of autonomic activity in the control of heart rate[All evaluated were performed at the same day]
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