Effects of WB-EMS and Protein Supplementation on LBM Maintenance During Intended Weight Loss
- Conditions
- OverweightAbdominal ObesityObesity
- Interventions
- Dietary Supplement: ProteinBehavioral: WalkingBehavioral: WB-EMS application
- Registration Number
- NCT03746977
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Brief Summary
The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women. Three study groups were implemented: (1) Protein supplementation (only) group (2) Protein supplementation and walking intervention (3) Protein supplementation, walking and WB-EMS-application. All protocols were applied for 16 week of intervention.
A energy deficit of 500 kcal/d was intended however while group (1) focus consistently on energy restriction (500 kcal/d), in group (2) and (3) a combined physical activity (i.e. walking with a volume representing 250 kcal/d) and energy restriction (250 kcal/d) protocol was applied. Total protein uptake including protein supplementation was calculated to average around 1.2 g/kg body mass per day in groups (1) and 1.5 g/kg body mass/d in group (2) and (3). WB-EMS was applied 1.5x 20 min/week (i.e. each Tuesday and every second Thursday).
Primary study endpoint was LBM as determined by Dual Energy x-Ray Absorptiometry.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 30
- premenopausal women 25-50 years old
- overweight/obesity (body fat rate equal or higher 30%)
- medication and diseases affecting muscle and fat metabolism
- pregnant or parturition < 6 months
- any condition or medication that prevent proper physical activity or WB-EMS application
- holidays equal or more than 1 week during the intervention period
- other interventions with impact on the primary and core secondary outcome (i.e. body fat parameters) started during the last year.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Energy restriction, walking and protein Walking Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d) and total protein uptake (including supplementation) of 1.5 g/kg body mass/d Energy restriction, walking and protein Protein Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d) and total protein uptake (including supplementation) of 1.5 g/kg body mass/d Energy restriction, walking, protein and WB-EMS WB-EMS application Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d), total protein uptake (including supplementation) of 1.5 g/kg body mass/d and WB-EMS application 1,5x 20 min/week energy restriction and protein supplementation Protein Energy restriction of 500 kcal/d and total Protein Uptake (including Supplementation) of 1.2 g/kg body mass/d Energy restriction, walking, protein and WB-EMS Protein Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d), total protein uptake (including supplementation) of 1.5 g/kg body mass/d and WB-EMS application 1,5x 20 min/week Energy restriction, walking, protein and WB-EMS Walking Energy restriction of 250 kcal/d, increased energy consumption by walking (250 kcal/d), total protein uptake (including supplementation) of 1.5 g/kg body mass/d and WB-EMS application 1,5x 20 min/week
- Primary Outcome Measures
Name Time Method Lean body mass changes from baseline to 16 week follow-up Fat and bone free total body mass in kg
- Secondary Outcome Measures
Name Time Method Visceral Body Fat changes from baseline to 16 week follow-up Total visceral body fat in kg
Trunk fat changes from baseline to 16 week follow-up Total trunk fat in kg
Total Body Fat changes from baseline to 16 week follow-up Total Body Fat in kg
Appendicular Skeletal Muscle Mass changes from baseline to 16 week follow-up Lean Body Mass of the upper and lower limbs in kg
Metabolic Syndrome Z-Score changes from baseline to 16 week follow-up Summarized Z-Score that included Z-Scores of blood lipids, lipoproteins, glucose, resting blood pressure and waist circumference. Cut-offs based on the definition of the International Diabetes Federations
Total Body Fat Rate changes from baseline to 16 week follow-up Percent Total Body Fat Rate
Trial Locations
- Locations (1)
Institute of Medical Physics University of Erlangen-Nurnberg
🇩🇪Erlangen, Germany