Efficacy of double dose influenza vaccine with a booster compare to standard dose in hemodialysis patients ; randomized controlled trial
Phase 3
Completed
- Conditions
- Allergy to component of vaccine
- Registration Number
- TCTR20190620001
- Lead Sponsor
- Goverment
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Patients undergoing hemodialysis
OPD at BAH
Age ≥ 18 years
Sp Kt/V ≥ 1.2
Hb ≥ 9 g/dL
Serum albumin ≥ 3 g/dL
Serum ferritin < 1,000 ng/mL
Exclusion Criteria
Immunocompromised host e.g. HIV
Taking any immunosuppressive agent for 3 months subsequent months before enrollment
Having been hospitalized for 3 months subsequent months before enrollment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of patients with seroprotection of influenza infection Before vaccination, 2 weeks and 4 weeks after vaccination Hemoagglutination inhibitor titer for influenza 4 strains
- Secondary Outcome Measures
Name Time Method Seroprotection and seroconversion 4 weeks after first vaccination Hemoagglutination inhibitor titer for influenza 4 strains