Comparison of the Anesthetic and Analgesic Efficacy of Selective Truncal Blocks at Different Volumes in Upper Extremity Orthopedic Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- on the onset times of motor and sensory blocks required for anesthesia
研究概览
简要总结
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist, forearm, and elbow surgeries. Completing the operation under regional anesthesia will be considered a successful block.
详细描述
The primary outcome of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist, forearm, and elbow surgeries. Completing the operation under regional anesthesia will be considered a successful block.
Secondary Outcome Variables:
Secondary outcomes include comparisons between the two groups regarding total motor block duration and analgesia durations, tourniquet pain, incidence of diaphragm paralysis, complications (vascular puncture, paresthesia, Horner's syndrome, hoarseness), time to first postoperative analgesic administration, and total analgesic consumption within the first 24 postoperative hours.
This study aims to compare the anesthetic efficacy and complication rates associated with different volumes of local anesthetic used in upper extremity surgeries (elbow, forearm, and hand surgeries) in patients over 18 years of age with ASA scores of 1-2 to reduce complication rates.
In recent years, brachial plexus blocks, performed through various approaches, have become preferred over general anesthesia for upper extremity surgeries due to numerous advantages. Peripheral nerve blocks are known to maintain patient consciousness and spontaneous breathing, reduce airway interventions, provide effective postoperative pain control, decrease opioid-related side effects, limit surgical stress-induced metabolic and endocrine changes, enable early discharge, and reduce treatment costs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body Mass Index (BMI) of 18-35 kg/m²
- •Age: 18-65 years -Patients undergoing all upper extremity orthopedic surgeries, except shoulder surgeries (distal humerus, elbow, forearm, hand, and wrist), will be included. -
排除标准
- •Patient refusal
- •Pregnancy or breastfeeding
- •Severe pulmonary disease
- •Contralateral diaphragm paralysis
- •Nerve injury secondary to trauma
- •Neuromuscular disease
- •Peripheral neuropathy
- •Bleeding diathesis
- •Allergy to local anesthetics and dexamethasone
- •Uncontrolled diabetes mellitus
- •Morbid obesity with BMI >35
- •Severe cardiovascular, renal, or hepatic disease
- •Infection at the site of the nerve block
结局指标
主要结局
on the onset times of motor and sensory blocks required for anesthesia
时间窗: 24 hour
The primary outcome of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist, forearm, and elbow surgeries. Completing the operation under regional anesthesia will be considered a successful block.
次要结局
- Total Opioid Consumption(24 hour)
- time to first rescue analgesic requirement.(24 hour)
- diaphragm paralysis(24 hour)
研究者
SERPİL ŞEHİRLİOĞLU
principal invertigator
Gaziosmanpasa Research and Education Hospital
