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临床试验/NCT06763510
NCT06763510已完成不适用

Comparison of the Effects of Two Different Local Anesthetics Used in Spinal Anesthesia

Ankara Ataturk Sanatorium Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2015年2月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1
主要终点
Temperature

研究概览

简要总结

Objective: This study aimed to compare the effects of two different local anesthetics with different baricity used in spinal anesthesia on thermoregulation.

Materials and Methods: The study was conducted on forty full-term pregnant women scheduled for elective cesarean sections under spinal anesthesia. At an operating room temperature of twenty-four degrees Celsius, peripheral body temperature was measured using temperature probes attached to the lower medial parts of the same side's lower and upper extremities, and central body temperature was measured with a tympanic thermometer. Isobaric levobupivacaine and hyperbaric bupivacaine were used in spinal anesthesia applications. After spinal anesthesia, tympanic temperature, arm and leg temperatures, mean arterial pressure, heart rate, and oxygen saturation were measured and recorded at baseline, the first, third, and fifth minutes, and every five minutes thereafter until the end of surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Term pregnant with elective cesarean section planned under spinal anesthesia
  • 18-40 years old

排除标准

  • patients in whom spinal anesthesia is contraindicated,
  • patients with neuromuscular disease,
  • alcohol and substance abusers,
  • patients with a body mass index (BMI) <18.5 kg/m² or >35 kg/m²,
  • those taking medications that may affect thermoregulation such as vasodilators,
  • patients with thyroid disease,
  • patients with fever and infection,
  • patients with known allergies to study drugs.

研究组 & 干预措施

Isobaric levobupivacaine

干预措施: Chirocaine (Drug)

Hyperbaric bupivacaine

干预措施: Bupivacaine (Drug)

结局指标

主要结局

Temperature

时间窗: During operation

Isobaric levobupivacaine or hyperbaric bupivacaine were used in spinal anesthesia applications. After spinal anesthesia, tympanic temperature, arm and leg temperatures were measured and recorded at the beginning, first, third and fifth minutes and then every five minutes until the end of the surgery.

次要结局

未报告次要终点

研究者

发起方
Ankara Ataturk Sanatorium Training and Research Hospital
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Azra Ozanbarci

specialist

Ankara Ataturk Sanatorium Training and Research Hospital

研究点 (1)

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