Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment

Completed

• Conditions: Acromegaly

• Registration Number: NCT01302652
• Lead Sponsor: Massachusetts General Hospital

Brief Summary

The purpose of this research study is to study the effects of growth hormone (GH) replacement on the heart. The investigators will study these effects in people who have been cured of acromegaly and then have developed growth hormone deficiency (GHD, not enough growth hormone).

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02
• Study First Submitted: 2011-02-18
• Study First Submitted QC: 2011-02-23
• Study First Posted: 2011-02-24
• Primary Completion: 2015-02
• Study Completion: 2015-02
• Status Verified: 2015-03
• Last Update Submitted: 2015-03-17
• Last Update Posted: 2015-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• age 18-75
• history of acromegaly with biochemical cure
• growth hormone deficiency

Exclusion Criteria

• untreated thyroid disease within the past 3 months
• untreated adrenal insufficiency within the past 3 months
• uncontrolled hypertension
• congestive heart failure
• gonadal steroid therapy within the past 3 months
• pregnancy or nursing

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change from Baseline in Echocardiographic Findings at One Year	baseline and one year

Trial Locations

Locations (1)

Massachusetts General Hospital; 🇺🇸 Boston, Massachusetts, United States