NCT01302652已完成不适用
Effects of Physiologic Growth Hormone Administration on Echocardiographic Parameters in Subjects With Growth Hormone Deficiency Following Cure of Acromegaly
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change from Baseline in Echocardiographic Findings at One Year
研究概览
简要总结
The purpose of this research study is to study the effects of growth hormone (GH) replacement on the heart. The investigators will study these effects in people who have been cured of acromegaly and then have developed growth hormone deficiency (GHD, not enough growth hormone).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-75
- •history of acromegaly with biochemical cure
- •growth hormone deficiency
排除标准
- •untreated thyroid disease within the past 3 months
- •untreated adrenal insufficiency within the past 3 months
- •uncontrolled hypertension
- •congestive heart failure
- •gonadal steroid therapy within the past 3 months
- •pregnancy or nursing
结局指标
主要结局
Change from Baseline in Echocardiographic Findings at One Year
时间窗: baseline and one year
次要结局
未报告次要终点
研究者
Karen Klahr Miller, MD
Principal Investigator
Massachusetts General Hospital
研究点 (1)
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