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Clinical Trials/NCT06296420
NCT06296420
Recruiting
Not Applicable

Dysphagia After Thyroidectomy

Istituto Auxologico Italiano1 site in 1 country420 target enrollmentJanuary 31, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Goiter
Sponsor
Istituto Auxologico Italiano
Enrollment
420
Locations
1
Primary Endpoint
The primary outcome measure will be the questionnaire which will be developed in the first phase of the study itself.
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

The goal of this observational study is to develop a questionnaire for measuring swallowing and throat discomfort symptoms in patients with goiter or thyroidectomy, which complies with the model of Rasch and which satisfies the fundamental measurement axioms (e.g., unidimensionality, linearity, generalizability). Developing a scale with such characteristics would provide clinicians and researchers with a reliable tool for assessing the impact of goiter and for measuring the outcomes after surgery.

Also, the study will assess the psychological impact of goiter and thyroidectomy, as well as the characteristics of the surgical scar after thyroidectomy.

The questionnaire will be developed in the first phase of the study. Items and response categories will be identified through interviews performed with patients affected by goiter or after thyroidectomy.

In the following phases of the study, the questionnaire will be administered to patients before and after thyroidectomy.

Registry
clinicaltrials.gov
Start Date
January 31, 2024
End Date
November 30, 2026
Last Updated
4 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of goiter or thyroidectomy.

Exclusion Criteria

  • Diagnosis of other neurological disorders or disorders involving the aerodigestive tract that could cause swallowing disorders.
  • Previous surgery of the neck or involving the aerodigestive tract.

Outcomes

Primary Outcomes

The primary outcome measure will be the questionnaire which will be developed in the first phase of the study itself.

Time Frame: In the week before surgery, three months after surgery, and six months after surgery.

The questionnaire will be administered to the recruited patients three times: in the week before surgery, three months after surgery, and six months after surgery.

Secondary Outcomes

  • Patient and Observer Scar Assessment Scale (POSAS) 2.0.(The POSAS 2.0 will be administered 10 days after surgery and 2 months after surgery.)
  • Depression Anxiety Stress Scales-21 (DASS-21).(The DASS-21 will be administered 10 days before surgery and 2 months after surgery.)

Study Sites (1)

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