Objective Analysis of Swallowing and Functional Voice Outcomes After Thyroidectomy: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 主要终点
- functional oral intake score
研究概览
简要总结
Impairment in voice and swallowing functions are common after thyroidectomy. The investigators aimed to evaluate the objective functional voice and swallowing outcomes in a series of patients undergoing thyroidectomy.
according to the study, even in the absence of recurrent laryngeal nerve injury, subjective and objective swallowing and voice alterations do occur after thyroidectomy.
详细描述
A total of 43 consenting patients who underwent thyroidectomy were prospectively recruited. Subjective evaluation of swallowing was assessed with 'Swallowing Impairment Score' and 'MD Anderson Dysphagia Inventory'. Fiberoptic endoscopic evaluation of swallowing (FEES) was applied for objective evaluation. Also, functional oral intake scale (FOIS) and functional outcome swallowing scale (FOSS) were used for swallowing assessment. Voice evaluation was assessed with videostrobolaryngoscopy (VSL) and 'The Multi-Dimensional Voice Program (MDVP)' was used for capturing and analyzing the voice samples. All evaluations were performed preoperatively and on 1st day, 2nd week and 6th months postoperatively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 27 Years 至 78 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients undergoing thyroidectomy
排除标准
- •Patients who were diagnosed with thyroid carcinoma preoperatively
- •Having history of previous neck surgery,
- •History of radiotherapy at head and neck region,
- •Vocal cord paralysis,
- •neuromuscular dysfunction,
- •larynx, esophagus and chest pathology
- •who did not want to be involved in the study
结局指标
主要结局
functional oral intake score
时间窗: 6 months
comparison of functional oral intake score of specific functional limitation between groups
voice evaluation
时间窗: 6 months
comparison of standard deviation of average, fundamental frequency and degree of subharmonics between groups
light and moderate residual accumulation in solid food intake
时间窗: 6 months
comparison of light and moderate residual accumulation in solid food intake between groups
the intake of fluid and thickened liquid food
时间窗: 6 months
comparison of the intake of fluid and thickened liquid food between pre- and post-operative scores
MD Anderson dysphagia inventory (MDADI)
时间窗: 6 months
comparison of MD Anderson dysphagia inventory (MDADI) between pre- and post-operative groups
Swallowing impairment score (SIS)
时间窗: 6 months
comparison of Swallowing impairment score (SIS) between pre- and post-operative groups
次要结局
- objective and subjective values correlation(6 months)
研究者
Ozer Makay
ass. prof. ozer makay
Ege University