The muscle activity of the diaphragm and intercostal muscles in acutely dyspneic children during hospitalization, before and after treatment with salbutamol

Completed

• Conditions: dyspnea; tightness of the chest; 10006436

• Registration Number: NL-OMON40181
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-02-01
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 55

Inclusion Criteria

Research group:
- Children from 0 months to 6 years who present with acute shortness of breath and treated with Sabutamol (sometimes combined with Ipratropium bromide). ;control group:
- Children from 0 months to 6 years
- From a nursery, after school care or school in the province of Groningen and Drenthe

Exclusion Criteria

research group:
- Congenital disorders that can cause distress and severe congenital heart disease or cystic fibrosis.
- Status after diaphragmatic hernia
- Allergy to EMG patches
- Prematurity
- Pneumonia ;control group:
- Congenital disorders or acquired diseases that can cause distress and severe congenital heart defects, cystic fibrosis, asthma, pneumonia.
- Use of bronchodilator agents
- Status after diaphragmatic hernia
- Allergy to EMG patches
- Prematurity

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main data obtained in this study are the EMG values **before and after<br /><br>treatment with Salbutamol in children with acute dyspnea.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome measure is the degree of dyspnea. This consists of the<br /><br>Clinical Asthma Score, determined by the investigator, and the Borg scale,<br /><br>determined by the parents. Beside, EMG values **of acutely distressed children<br /><br>will be compared with EMG values **in healthy peers.</p><br>