Comparison of thickness of diaphragm in patients receiving two different types of mechanical ventilation for acute respiratory failure
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Acute respiratory failure
- Registration Number
- CTRI/2018/05/013714
- Lead Sponsor
- Sulagna Bhattacharjee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Patients with acute respiratory failure requiring mechanical ventilation for at least three days or more admitted in an intensive care unit (ICU) of a tertiary care teaching hospital (AIIMS, New Delhi)
Patients who have been receiving mechanical ventilation for less than 12 hours before recruitment will be included in this study
Exclusion Criteria
1.Patients suffering from neuromuscular diseases
2.Use of neuromuscular blockade to facilitate mechanical ventilation
3.BMI less than 18.5kg/m2
4.Obesity (BMI more than 30kg/m2)
5.Severe ARDS (as per Berlin definition)
6.Previous chest wall surgery
7.Pregnancy
8.History of mechanical ventilation in the past 3 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the change in diaphragmatic thickness at day 3 between patients on SIMV-PS ventilation & PRVC ventilationTimepoint: To compare the change in diaphragmatic thickness at day 3 between patients on SIMV-PS ventilation & PRVC ventilation
- Secondary Outcome Measures
Name Time Method 1.The change in diaphragmatic thickness at day 1, 2,& 7 between patients on SIMV-PS ventilation & PRVC ventilation <br/ ><br>2.The change in diaphragmatic thickness at the time of extubation between patients on SIMV-PS ventilation & PRVC ventilation <br/ ><br>3.The change in quadriceps muscle thickness at day 1,2,3 &7 between patients on SIMV-PS ventilation & PRVC ventilation <br/ ><br>4.The length of ICU stay & ICU mortality between two groups of patients <br/ ><br>Timepoint: Days 1,2,3 & 7