Effects of voluntary apnea on the cardiovascular system
- Conditions
- Basic science: Evaluation of voluntary Apnoea and ist effects on the cardiovascular, cerebral and hormonal system
- Registration Number
- DRKS00021448
- Lead Sponsor
- niversitätsklinikum Bonn
- Brief Summary
Although, prolonged apnea leads to impressive adaptions of the cardiovascular system (i.e. dilation of the left ventricle) and hypertension due to peripheral vasoconstriction no mid-term morphological changes could be observed in both, the myocardium and the brain. BH divers are suitable as a model to investigate acute physiological changes of prolonged apnea and hypoxemia, but not as a model for chronic alterations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
healthy subjects
Exclusion Criteria
pre-existing conditions
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Create a set of cerebral and myocardial MRI-data during an post maximal voluntary apnea. Follow up after 12-14 months.
- Secondary Outcome Measures
Name Time Method Analyse of blood-cells and Hormons after a maximal dry apnea.