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临床试验/NCT01779245
NCT01779245已完成不适用

The Impact of a Calcium Supplementation on Lipid Metabolism During Exercise.

Northumbria University1 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2012年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
13
试验地点
1
主要终点
Substrate metabolism

研究概览

简要总结

A high-calcium intake can accelerate fat loss under energy-restricted diets. Part of this may be due to a shift in substrate metabolism where there is an increase in the rate of fat oxidation. However, whether high-calcium intake can influence substrate metabolism during exercise is not known. Accordingly, we aim to investigate the effect of 2 weeks of high-calcium intake on substrate metabolism during exercise.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •Physically active (moderate-vigorous exercise >3 time per week)
  • •18-40 yrs of age

排除标准

  • •Known Food Allergies
  • •Metabolic disorders

研究组 & 干预措施

Control

Placebo Comparator

A chocolate milkshake with a normal calcium content will be consumed daily (235 kcal; 13 g protein; 42 g carbohydrate; 1 g fat, 400 mg calcium per serving).

干预措施: Placebo (Dietary Supplement)

High-Calcium

Experimental

A chocolate milkshake with a high calcium content will be consumed daily (235 kcal; 13 g protein; 42 g carbohydrate; 1 g fat, 1400 mg calcium per serving).

干预措施: Calcium (Dietary Supplement)

结局指标

主要结局

Substrate metabolism

时间窗: 60 s samples every 3 min for 15 min

Substrate metabolism will be assessed by the respiratory exchange ratio (rate of carbon dioxide production/rate of oxygen consumption) from samples of expired gas collected during the first 15 minutes of an incremental cycling test.

次要结局

  • Plasma non-esterified fatty acid concentrations(Every 3 min for 15 min)
  • Plasma glycerol concentrations(Every 3 min for 15 min)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Javier Gonzalez

Principal Investigator

Northumbria University

研究点 (1)

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