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Prevalence and Risk Factors of Non-Diabetic Kidney Disease in Type 2 Diabetes Patients with Nephrotic Range Proteinuria

Completed
Conditions
Etiology of nephrotic-range proteinuria in type 2 diabetes mellitus patient
Type 2 diabetes mellitus, kidney biopsy, diabetic kidney disease, nephrotic syndrome
Registration Number
TCTR20230927003
Lead Sponsor
Vajira hospital, Navamindradhiraj University
Brief Summary

The prevalence of any NDKD with or without DN is 67%. A clinical prediction score for distinguishing any NDKD from DN alone can defer kidney biopsy. Absence of diabetic retinopathy, Age more than 50 years, duration of DM less than 6 years, and absence of hypertension have significant association with any NDKD.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
273
Inclusion Criteria

Type 2 diabetes meliitus
- Indications for biopsy due to albuminuria of more than 3 g per day.

Exclusion Criteria

- Kidney transplant patients.
- Patients whose kidney tissues were not appropriately sampled.
- Patients with incomplete medical records such as unclear diabetes diagnosis history, chronic disease history, diabetic retinopathy test history, laboratory and kidney ultrasound test results.
- Patients with a history of or physical test results indicating a systemic disease or other clear glomerulus causes.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Prevalence of other glomerular disease in type 2 diabetes mellitus with nephrotic range proteinuria At the time of kidney biopsy Prevalence
Secondary Outcome Measures
NameTimeMethod
Risk factors of non-diabetic glomerular disease At the time of kidney biopsy Risk factors
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