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临床试验/NCT06396351
NCT06396351已完成不适用

Factors Influencing Abdominal Compliance During CO2 Insufflation in Patients Undergoing Laparoscopic Abdominal Surgery

Ankara University1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2022年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
90
试验地点
1
主要终点
The factors affecting abdominal compliance

研究概览

简要总结

The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

详细描述

During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC.

The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 82 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique

排除标准

  • Aged below 18 and above 82 ASA IV-V

结局指标

主要结局

The factors affecting abdominal compliance

时间窗: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

Effect of rectus muscle thickness and lateral abdominal muscle group thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

次要结局

  • The factors affecting abdominal compliance(From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sanem Cakar Turhan

Associate professor, MD

Ankara University

研究点 (1)

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