Vruchtbaarheid, eicelvoorraad en vervroegde overgang bij Nederlandse vrouwen die in hun jeugd kanker hebben gehad .
Recruiting
- Conditions
- childhood cancer , fertility, ovarian reserve, premature menopause
- Registration Number
- NL-OMON25491
- Lead Sponsor
- VU University Medical Center Amsterdam
- Brief Summary
Van den Berg MH, van Dulmen-den Broeder E, Overbeek A, Twisk JW, Schats R, van Leeuwen FE, Kaspers GJ, Lambalk CB.<br> Comparison of ovarian function markers in users of hormonal contraceptives during the hormone-free interval and subsequent natural early follicular phases. Hum Reprod. 2010 Jun;25(6):1520-7.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 2000
Inclusion Criteria
1. Female;
2. Treated for malignancy or a central nervous system tumour before the age of 18;
Exclusion Criteria
1. Being unable to speak or read Dutch;
2. Having severe mental sequelae;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Questionnaire part: Reproductive history, pregnancy outcomes, menopausal symptoms and menopause;<br /><br>2. Clinical part: FSH, Estradiol, inhibin B, AMH, <br>ovarian reserve.
- Secondary Outcome Measures
Name Time Method 1. Questionnaire part: Co-morbidities, menstrual history, family history of subfertility;<br /><br>2. Clinical part: Ovarian volume, uterus flow, uterus length.