Venous Function in Cardiovascular Disease Patients

Not Applicable

Completed

• Conditions: Myocardial Infarction
• Interventions: Behavioral: interval training day 1; Behavioral: Moderate exercise day 2; Behavioral: Control day 3

• Registration Number: NCT01474408
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched healthy subjects.

Detailed Description

Compare the effect of 4 x 4 minutes at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate and moderate continuous exercise at 70 % of peak heart rate on venous function.

Study Timeline

• Study Start: 2011-11
• Study First Submitted: 2011-11-04
• Study First Submitted QC: 2011-11-15
• Study First Posted: 2011-11-18
• Primary Completion: 2012-11
• Study Completion: 2012-11
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-13
• Last Update Posted: 2017-02-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• myocardial infraction (MI)
• revascularization (PCI)
• coronary artery bypass graft surgery (CABG)

Exclusion Criteria

• unstable angina pectoris
• uncontrolled hypertension
• orthopedic and/or neurological limitations
• participation in other studies
• MI (closer than 4 weeks)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
control	Moderate exercise day 2	routine measurements, no exercise
interval training	Moderate exercise day 2	4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
moderate exercise	interval training day 1	moderate continuous exercise at 70 % of peak heart rate on venous function.
interval training	interval training day 1	4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
interval training	Control day 3	4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
control	interval training day 1	routine measurements, no exercise
control	Control day 3	routine measurements, no exercise
moderate exercise	Moderate exercise day 2	moderate continuous exercise at 70 % of peak heart rate on venous function.
moderate exercise	Control day 3	moderate continuous exercise at 70 % of peak heart rate on venous function.

Primary Outcome Measures

Name	Time	Method
Venous Compliance change	48 hours	Measured by echocardiography

Trial Locations

Locations (1)

Institutt for Sirkulasjon og Bildetechnikk, NTNU; 🇳🇴 Trondheim, Norway