Clinical Trials
491
30 active
Approvals
0
Total approvals
Agencies
0
Regulatory bodies
Founded
1996
Active, not recruiting
23
4.7%
Completed
360
73.3%
Enrolling By Invitation
2
0.4%
Not yet recruiting
5
1.0%
Recruiting
43
8.8%
Terminated
37
7.5%
Unknown
6
1.2%
Withdrawn
15
3.0%
No approval data available
- A one-year hybrid exercise intervention reduced atrial fibrillation burden by 45% compared with usual care (3.9% vs. 7.1%; p=0.016) in the NEXAF trial presented at ESC Congress 2026. - The intervention improved cardiorespiratory fitness and resting heart rate, and was associated with 37% fewer total hospitalizations and 46% fewer AF-related hospitalizations. - No significant difference in AF-specific quality of life was observed between groups (AFEQT score: +5.6 vs. +4.4; p=0.43). - Researchers say the hybrid model combining short-term supervision with home-based exercise and digital support was clinically feasible and strengthens the case for structured exercise in AF care.
- Researchers at NTNU and St. Olav's University Hospital performed patient-matched transcriptomic comparison of in vivo and in vitro colonic epithelium from ulcerative colitis patients. - The study substantiates the fidelity of in vitro colonic epithelial models for studying inflammatory bowel disease at the molecular level. - Findings support the use of patient-derived organoid systems for precision medicine approaches in IBD, including drug screening and biomarker discovery. - The work was conducted under the Clinical Academic Group for Precision Medicine in Inflammatory Bowel Disease (CAG-IBD) initiative.
- New research from Norwegian University of Science and Technology demonstrates women experience more severe early PTSD symptoms than men, particularly in re-experiencing and avoidance symptom clusters. - The study analyzed 475 participants who experienced recent trauma, revealing significant gender differences in symptom networks and interconnections between PTSD manifestations. - While men showed stronger connections between anxious arousal and avoidance, women exhibited more robust links between re-experiencing and avoidance symptoms, suggesting gender-specific treatment approaches may be beneficial.
