Venous Function in Cardiovascular Disease Patients; The Neglected Part of Circulatory Regulation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Venous Compliance change
研究概览
简要总结
The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched healthy subjects.
详细描述
Compare the effect of 4 x 4 minutes at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate and moderate continuous exercise at 70 % of peak heart rate on venous function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •myocardial infraction (MI)
- •revascularization (PCI)
- •coronary artery bypass graft surgery (CABG)
排除标准
- •unstable angina pectoris
- •uncontrolled hypertension
- •orthopedic and/or neurological limitations
- •participation in other studies
- •MI (closer than 4 weeks)
研究组 & 干预措施
interval training
4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
干预措施: interval training day 1 (Behavioral)
interval training
4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
干预措施: Moderate exercise day 2 (Behavioral)
interval training
4 x 4 minutes exercise at 90 - 95 % of peak heart rate separated with 3 minutes at 70 % of peaks heart rate
干预措施: Control day 3 (Behavioral)
moderate exercise
moderate continuous exercise at 70 % of peak heart rate on venous function.
干预措施: interval training day 1 (Behavioral)
moderate exercise
moderate continuous exercise at 70 % of peak heart rate on venous function.
干预措施: Moderate exercise day 2 (Behavioral)
moderate exercise
moderate continuous exercise at 70 % of peak heart rate on venous function.
干预措施: Control day 3 (Behavioral)
control
routine measurements, no exercise
干预措施: interval training day 1 (Behavioral)
control
routine measurements, no exercise
干预措施: Moderate exercise day 2 (Behavioral)
control
routine measurements, no exercise
干预措施: Control day 3 (Behavioral)
结局指标
主要结局
Venous Compliance change
时间窗: 48 hours
Measured by echocardiography
次要结局
未报告次要终点