Treatment Of Gum Disease Using Blood units And Tissue derivatives

Not Applicable

Completed

• Conditions: screeing intervention

• Registration Number: CTRI/2018/10/016189
• Lead Sponsor: Angelin Rejoice

Brief Summary

The study is an randomized clinical trial, aimed to find the efficacy of platelet rich fibrin matrix and collagen membrane on miller’s class I and class II gingival recession. 20 identical bilateral recession defects will be selected and randomly allocated in to Group A ( collagen membrane) and Group B ( PRFM). The procedure will be explained to the patient and  informed consent is obtained. In the presurgical phase, scaling and re-evaluation carried on follwed by coronally advanced flap and placement of membrane or PRFM  according to the desired site,  followed by placement of periodontal dressing. Post-operative instructions are given, along with prescription of antibiotics, analgesics and chlorhexidine mouth wash. The study duration of two years, the clinical parameters will be recorded at baseline, 3 months and 6 months.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-24
• Study Completion: 2019-04-01
• Last Update Posted: 2020-03-07

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• 1 Systemically healthy subjects.
• 2 Age: 18-50 years.
• 3 Identical bilateral Miller’s class I and II isolated gingival recession.
• 4 Patients with more than 1mm of width of keratinized gingiva.
• •Presence of good oral hygiene maintenance.

Exclusion Criteria

• 1 History of subjects who underwent previous periodontal surgery for past 6 month.
• 2 Presence of dehiscence or fenestration.
• 3 Malposed / rotated teeth/ root caries.
• 4 Smokers and chewers of tobacco.
• 5 Pregnant or lactating mother.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Recession width at cemento-enamel junction.	baseline, 3months, 6 months
•Clinical attachment level.	baseline, 3months, 6 months
•Probing depth.	baseline, 3months, 6 months
•Recession depth	baseline, 3months, 6 months
•Keratinized gingival width.	baseline, 3months, 6 months

Secondary Outcome Measures

Name	Time	Method
Gingival index, Plaque index	Baseline, 3months, 6 months
. Assessment of soft tissue healing	. 1 week, 3 months, 6 months

Trial Locations

Locations (1)

The oxford dental college; 🇮🇳 Bangalore, KARNATAKA, India

The oxford dental college

🇮🇳Bangalore, KARNATAKA, India

Angelin Rejoice

Principal investigator

9620977991

angelinrejoicejohn@gmail.com