Short-, and long-term effects of the intra-operative nitrous oxide administration on the remifentanil-induced post-operative hyperalgesia, morphine consumption and long-term quality of life - nitrous oxide administration on the post-operative hyperalgesia

AIR LIQUIDE SANTE INTERNATIONA0 个研究点目标入组 138 人开始时间: 2006年7月7日最近更新: 2014年10月7日

试验速览

暂无简介。

•- types of surgery interventions: major abdominal surgeries with laparotomy of expected length of 4 hours or even specified
•- adults: 18 to 65 years old
•- ASA 1-3
•- signed patient consent form
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•-Thoracic surgery
•-Psychotropic agent chronic usage
•-Chronic pain or chronic use of opioid analgesic
•-Preceding major abdominal surgery
•-Expected prolonged intubation
•-Radiation in the area of surgery
•-Regular intake of analgesics (except low dose acetylic acid for cardiovascular reasons)
•-Opioid intake 24 hours before surgery
•-Major obesity (BMI > 30)
•-Drug or alcohol abuse
•-Incapability of handling of PCA
•-Instable or significant central nervous system, cardiac, hepatic, renal or endocrine dysfunction and/or significant sequelas
•-Product-related exclusion criteria.

发起方

AIR LIQUIDE SANTE INTERNATIONA