ISRCTN34631378
Completed
Not Applicable
The short- and long-term effects of perioperative gabapentin use on functional, rehabilitation and pain outcomes following total knee arthroplasty: a randomised, double-blind, placebo-controlled trial
Sunnybrook Health Sciences Centre (Canada)0 sites184 target enrollmentOctober 25, 2005
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Rehabilitation medicine and perioperative pain control
- Sponsor
- Sunnybrook Health Sciences Centre (Canada)
- Enrollment
- 184
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Upon obtaining informed consent, patients with American Society of Anesthesiologists physical status I and II, of both genders, scheduled for total knee arthroplasty will be recruited for this double\-blinded, prospective, randomised, and placebo\-controlled study. Patients must also be 18?75 years of age.
Exclusion Criteria
- •1\. Patients not providing informed consent
- •2\. Patients less than 18 years of age and greater than 75 years of age
- •3\. Known allergy to any of the medications being used
- •4\. History of drug or alcohol abuse
- •5\. Patients with chronic pain on slow\-release preparations of opioid
- •6\. Patients with Rheumatoid Arthritis
- •7\. Patients with psychiatric disorders
- •8\. Patients unable or unwilling to use Patient Controlled Analgesia (PCA)
- •9\. Diabetic patients or those with impaired renal function (Creatinine \>106\)
- •10\. Obese patients (i.e., body mass index \[BMI] \>40\)
Outcomes
Primary Outcomes
Not specified
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