evaluation of the effect of duloxetine in reducing pai
Not Applicable
Recruiting
- Conditions
- Evaluation of the Perioperative and Postoperative effects of Duloxetine in reducing postoperative pain in patients with spinal stenosis.Spinal stenosisM48.0
- Registration Number
- IRCT20210124050130N1
- Lead Sponsor
- Islamic Azad University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 64
Inclusion Criteria
all patients with spinal stenosis
Exclusion Criteria
Allergy to the test drug
Abnormal liver and kidney function test
Use of opioids, gabapentin and pregabalin for more than three months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umeric rating scale according to visual analogue scale. Timepoint: visual analogue scale before surgery and 2 hours after surgery and 24 hours after surgery. Method of measurement: by visual analogue scale criterion.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie duloxetine's analgesic effects in spinal stenosis postoperative pain management?
How does duloxetine compare to NSAIDs or opioids in reducing postoperative pain for spinal stenosis patients in IRCT20210124050130N1?
Which biomarkers correlate with duloxetine response in spinal stenosis (M48.0) patients undergoing surgical intervention?
What adverse events are associated with duloxetine use in spinal stenosis patients during perioperative and postoperative phases?
Are there combination therapies involving duloxetine and other SNRIs that enhance postoperative pain relief in spinal stenosis cases?