Role of Anesthesia / Surgery on Cognitive Function in Child
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Behavioral
- Sponsor
- Konstanze Plaschke
- Locations
- 1
- Primary Endpoint
- Global cognitive abilities
- Status
- Withdrawn
- Last Updated
- 5 years ago
Overview
Brief Summary
The role of surgical stress and anesthesia is unknown in the early childhood. In vitro and animal studies showed a risk for treatment with anesthesia in the developmental brain. Furthermore, stress is also an important risk factor for cognitive impairment. Therefore, the investigators want to investigate in a clinical prospective cohort study the role anesthesia and surgery on different cognitive parameters and self-controling mechanisms in children under 3 years.
Detailed Description
In order to investigate the role of anesthesia and / or surgery on cognitive abilities the investigators want to perform a prospective cohort study in children under 3 years. Three groups should be compared: i) control without anesthesia / surgery, ii) children with only anesthesia, and iii) children with both surgery and anesthesia. All children will be investigate before and after intervention. Different behavioral scales will be used for detailed cognitive abilities and self-regulatory skills.
Investigators
Konstanze Plaschke
Prof.
Heidelberg University
Eligibility Criteria
Inclusion Criteria
- •Age 9 month to 3 years with or without anesthesia / surgery
Exclusion Criteria
- •Psychiatrical, neurological, oncological diseases
Outcomes
Primary Outcomes
Global cognitive abilities
Time Frame: 4-6 weeks
Early Childhood Behavior Questionnaire (ECBQ) questionnaire
Secondary Outcomes
- surgery-associated data(1 day)