NL-OMON38102
Completed
Phase 4
The effects of anaesthesia on neurodevelopmental outcome and apnoe in infants: the GAS study. - GAS study
niversitair Medisch Centrum Utrecht0 sites40 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- anesthesiologie
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 40
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Any infant scheduled for unilateral or bilateral inguinal hernia repair (with or without circumcision)
- •Any infant whose gestational age (GA) is 26 weeks or more
- •Any infant whose post\-menstrual age (PMA) is up to 60 weeks.
Exclusion Criteria
- •1\. Any child older than 60 weeks post\-menstrual age
- •2\. Any child born at less than 26 weeks gestation
- •3\. Any contraindication to general or spinal/caudal anaesthesia (for example: neuromuscular disorder or coagulopathy)
- •4\. Pre\-operative ventilation immediately prior to surgery
- •5\. Congenital heart disease that has required surgery or will require surgery or which requires ongoing pharmacotherapy
- •6\. Known chromosomal abnormality or any other known acquired or congenital abnormalities (apart from prematurity) which are likely to affect development
- •7\. Children where follow\-up would be difficult for geographic or social reasons
- •8\. Families where Dutch is not the language spoken at home
- •9\. Known neurological injury such as cystic periventricular leukomalacia (PVL), or grade 3 or 4 intra\-ventricular haemorrhage (IVH) (\+/\- post\-haemorrhage ventricular dilatation)
- •10\. Previous exposure to volatile anaesthesia or benzodiazepines as a neonate or in the third trimester in utero
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
General Anesthesia exposure and neurodevelopmental outcome in Pediatrics.brain developmentNeurodevelopmental outcome1002930510043413NL-OMON54873Academisch Medisch Centrum70
Completed
Not Applicable
Effect of Anesthesia on Neurocognitive Function in Children 1-36 Months; the Preliminary StudyTCTR20211209006Faculty of Medicine Siriraj hospital69
Completed
Not Applicable
Studying the effect of anaesthesia on cerebral oxygen saturation using near infra red spectroscopy monitor in pre-eclampsia patients undergoing caesarean sectioHealth Condition 1: O149- Unspecified pre-eclampsiaCTRI/2019/04/018794Jawaharlal Institute of Postgraduate Medical Education and Research56
Unknown
Not Applicable
Anaesthesia and ApoptosisApoptosisNCT04431505Assiut University20
Active, not recruiting
Phase 3
A Study to Compare the Long-term Outcomes After Two Different AnaestheticsAnesthesiaNeurotoxicityChild DevelopmentNCT03089905Murdoch Childrens Research Institute450