The effects of anaesthesia on neurodevelopmental outcome and apnoe in infants: the GAS study. - GAS study

niversitair Medisch Centrum Utrecht0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Any infant scheduled for unilateral or bilateral inguinal hernia repair (with or without circumcision)
•Any infant whose gestational age (GA) is 26 weeks or more
•Any infant whose post-menstrual age (PMA) is up to 60 weeks.

•1. Any child older than 60 weeks post-menstrual age
•2. Any child born at less than 26 weeks gestation
•3. Any contraindication to general or spinal/caudal anaesthesia (for example: neuromuscular disorder or coagulopathy)
•4. Pre-operative ventilation immediately prior to surgery
•5. Congenital heart disease that has required surgery or will require surgery or which requires ongoing pharmacotherapy
•6. Known chromosomal abnormality or any other known acquired or congenital abnormalities (apart from prematurity) which are likely to affect development
•7. Children where follow-up would be difficult for geographic or social reasons
•8. Families where Dutch is not the language spoken at home
•9. Known neurological injury such as cystic periventricular leukomalacia (PVL), or grade 3 or 4 intra-ventricular haemorrhage (IVH) (+/- post-haemorrhage ventricular dilatation)
•10. Previous exposure to volatile anaesthesia or benzodiazepines as a neonate or in the third trimester in utero

发起方

niversitair Medisch Centrum Utrecht