Anaesthesia and Apoptosis

• Conditions: Apoptosis

• Registration Number: NCT04431505
• Lead Sponsor: Assiut University

Brief Summary

Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-06-11
• Study First Submitted QC: 2020-06-11
• Study Start: 2020-06-12
• Study First Posted: 2020-06-16
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-14
• Last Update Posted: 2020-07-16
• Primary Completion: 2020-12-01
• Study Completion: 2020-12-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• congenital heart corrective surgery

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
apoptotis during anaesthesia	24 hours	measuring markers of apoptosis pathway

Trial Locations

Locations (1)

Assiut university; 🇪🇬 Assiut, Egypt