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临床试验/NCT03029052
NCT03029052已完成不适用

A Comparative Pilot Study in an Infectious Disease Department Assessing the Impact of Medication Reconciliation at Discharge Associated With a Patient's Counseling Session, Both Provided by a Pharmacist, on Patient's Care After Discharge

Centre d'Investigation Clinique et Technologique 8052 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2017年2月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
120
试验地点
2
主要终点
Proportion of in-hospital prescription changes not maintained by the Primary Care Physician (PCP) one month after discharge.

研究概览

简要总结

Patient's discharge from hospital is associated with iatrogenic events for 12 to 17% of patients. This risk may be linked with discontinuity of care between hospital physicians and Primary Care Physician (PCP). The investigators aim to assess in this study the impact of medication reconciliation at discharge associated with a patient's counseling session, both provided by a pharmacist, on patient's care after discharge. To demonstrate the interest of medication reconciliation at discharge we expect a reduction by 15% of the number of prescription changes not maintained by the PCP after discharge.

详细描述

Patient's discharge from hospital is associated with iatrogenic events for 12 to 17% of patients and may lead to further hospitalization. This risk may be linked with discontinuity of care between hospital physicians and Primary Care Physician (PCP) and from discrepancies between patient's current medications and drugs prescribed at discharge.

Preventing adverse drug events (ADEs) remains a patient safety priority not only in hospitals but also across the continuum of care for patients. Implementing medication reconciliation at all transitions in care is an effective strategy for preventing discrepancies and ADEs. Medication reconciliation prevents and corrects medication errors by promoting transmissions of complete and accurate information about medicines.

Furthermore, ADEs may be the result of a failure to understand and manage post-discharge care needs and can lead to hospital readmission.

We assume that medication reconciliation at discharge, secondarily transmitted to the PCP with a discharge counseling session between the patient and a clinical pharmacist could have a positive impact on the maintenance of therapeutic optimization decided by in-hospital practitioners.

In order to evaluate this assumption, we will conduct a randomized controlled study on 120 patients (as a reduction by 15% of the number of prescription changes not maintained by the PCP after discharge is expected).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age ≥ 18 years old
  • hospitalized in infectious disease department
  • with a chronic disease and a current medical prescription including at least three drugs
  • discharged home or nursing home
  • not opposed to the study

排除标准

  • foreigners, patients under legal guardianship
  • advanced dementia (MMS<20) or phone tracking impossible
  • primary care physician opposed to answer questionnaire

结局指标

主要结局

Proportion of in-hospital prescription changes not maintained by the Primary Care Physician (PCP) one month after discharge.

时间窗: 1 month

The number of in-hospital prescription changes will be evaluated only on discharge prescription transmitted to the patient (after prescription analysis by a clinical pharmacist in the "reconciliation" group) Compared to the list of all current medications at admission, in-hospital prescription changes include the following: * Adding a new drug * Discontinuing a drug * Drug switch * Modifying a dose Among these hospital prescription changes, some will not be maintained by the PCP one month after discharge. In-hospital prescription changes not maintained by the PCP will be evaluated on the first prescription of the PCP following discharge.

次要结局

未报告次要终点

研究者

发起方
Centre d'Investigation Clinique et Technologique 805
申办方类型
Other
责任方
Principal Investigator
主要研究者

Frederique Bouchand

PharmD

Centre d'Investigation Clinique et Technologique 805

研究点 (2)

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