A STUDY ON CHILDREN SUFFERING FROM NUTRITIONAL RICKETS AGED 6 MONTHS TO 5 YEARS COMPARING A LOWER DOSE OF VITAMIN D GIVEN AS A SINGLE ORAL DOSE FOR TREATMENT (90,000IU) WITH THE STANDARD DOSE (3,00,000 IU)
Not Applicable
Completed
- Conditions
- Health Condition 1: null- CHILDREN AGED 6 MNTHS TO 5 YRS WITH NUTRITIONAL RICKETS EXCLUDIN SEVERE SYSTEMIC ILLNESS,ON CALCIUM OR VITAMIN D SUPPLEMENTS,FEATURES OF MALABSORPTIO
- Registration Number
- CTRI/2017/02/007791
- Lead Sponsor
- CHACHA NEHRU BAL CHIKITSALYA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 106
Inclusion Criteria
PATIENTS AGED 6 MONTHS TO 5 YEARS WITH BIOCHEMICAL AND RADIOLOGICAL DIAGNOSIS OF RICKETS PRESENTING TO OPD OR ADMITTED AT IPD IN DEPARTMENT OF PEDIARICS AT CHACHA NEHRU BAL CHIKITSALYA
Exclusion Criteria
1)PATIENTS WITH SUSPECTED OR CONFIRMED DIAGNOSIS OF MALABSORPTION
2)PATIENTS WITH SEVERE SYSTEMIC ILLNESS COMPROMISING ORAL INTAKE(TACHYCARDIA,TACHYPNEA,SHOCK,WEAK PERIPHERAL PULSES)
3)PATIENTS WHO HAVE TAKEN CALCIUM OR VITAMIN D SUPPLEMENT IN LAST 6 MONTHS
4)PATIENTS WITH CLINICAL OR BIOCHEMICAL MARKERS SUGGESTIVE OF RICKETS OTHER THAN NUTRITIONAL RICKETS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RADIOLOGICAL HEALING AT 90 DAYSTimepoint: RADIOLOGICAL HEALING AT 90 DAYS
- Secondary Outcome Measures
Name Time Method 1)SIDE EFFECT PROFILE USING CALCIUM/CREATININE i.e. HYPERCALCIURIATimepoint: 7-10th DAY,30-37th DAY,90-97th day;DECLINE IN ALP LEVELTimepoint: 30-37TH DAY,90-97TH DAY;DECLINE IN PTH LEVELTimepoint: 90 DAYS;INCREASE IN 25(OH)DTimepoint: 90 DAYS