Comparison of the efficacy between the additional local anesthetic peri-femoral artery injection with the combined femoral and sciatic nerve block and the combined femoral and sciatic nerve block for thigh tourniquet-induced hypertension during lower limbs surgery: A randomized control trial
Phase 2
- Conditions
- tourniquet hypertension in patients undergoing lower limbs surgerytourniquet hypertension, peri-arterial injection, perifemoral artery, tourniquet intolerance, femoral nerve block, sciatic nerve block
- Registration Number
- TCTR20210524009
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. patients undergoing lower limbs surgery
2. American Society of Anesthesia 1-2
3. patients weighted more than 60 kilograms
Exclusion Criteria
1. patient refusal
2. diagnosis of chronic opioid use
3. intolerance or allergy to local anesthetic drugs
4. weight less than 60 kilograms
5. American Society of Anesthesia more than 2
6. pregnancy
7. patients with an inability to communicate pain scores
8. patients with contraindication of applying tourniquets
9. patients with high risks of local anesthetic toxicity
10. patients with uncontrolled hypertension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method tourniquet hypertension intraoperative Measuring systolic blood pressure using a cuff, aim to keep within 30% change from baseline
- Secondary Outcome Measures
Name Time Method Pain Scores in PACU until one day after surgery The Numeric Rating Scale,Amount of Opioid Medications (fentanyl) Used by Patient intraoperative and during at PACU Amount of opioid pain medication used by patient,Amount of nicardipine used intraoperatively intraoperative period Amount of nicardipine (in mg) used intraoperatively to decrease blood pressure after subject achieved tourniquet hypertension.,quadriceps muscle strength at PACU,postoperative day 1 digital dynamometer,postoperative nausea and vomiting postoperative day 0-2 visual analog scale