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A comparison of the effectiveness of additional injections of opioid and anaesthetic in emergency root canal treatment of adultlower teeth

Phase 3
Completed
Conditions
Health Condition 1: K040- Pulpitis
Registration Number
CTRI/2019/05/018900
Lead Sponsor
nil
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
34
Inclusion Criteria

1. Healthy adults (ASA-I or ASA-II), aged between 18 â?? 65 years, who signed consent form.

2. Symptomatic irreversible pulpitis of the mandibular first or second molar.

a) The patients who have pain in a mandibular molar (visual analog scale >54) with prolonged response to cold testing (lingering pain for more than 45 seconds).

b) Absence of any periapical radiolucency on a periapical radiograph (except for a widened periodontal ligament of no more than 0.75â??1 mm and no pain on percussion).

3. Vital teeth with no history of previous root canal therapy.

4. Ability to understand the consent forms and the pain record scales.

Exclusion Criteria

1. A known allergy, sensitivity, or contraindications to any local anaesthetics or opioids. Those patients who show any abnormal reaction to the test dose of the drugs.

2. History of seizures, systemic diseases such as diabetes, uncontrolled hypertension, acute or severe bronchial asthma, significant respiratory depression, decreased renal or liver function.

3. Pregnancy or lactation.

4. History of narcotics or psychotic drugs, patients who had taken NSAIDs or sedatives within 24 hours before the root canal treatment.

5. Patients experiencing pain in more than 1 mandibular molar.

6. During the procedure, patients will be excluded if lip numbness is not achieved after the inferior alveolar nerve block.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Modified Heft Parker Visual Analog Scale pain scoreTimepoint: 1) Pre-operative pain score <br/ ><br>2) Intra-operative pain score <br/ ><br>3) Post-operative pain score after 6 hours <br/ ><br>4) Post-operative pain after 12 hours <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Heart rateTimepoint: Intra-operative
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